Postdoctoral Researcher in Cancer Biology and Therapeutics

Updated: 3 months ago

Do you want to contribute to improving human health?

The research team of Assistant Professor Sean Rudd is seeking to recruit a postdoctoral researcher. Dr Rudd’s team conducts multidisciplinary research with the goal of improving treatment outcome for cancer patients. Housed within the well-established laboratory of Professor Thomas Helleday , this research team has obtained generous funding from the Swedish Research Council, the Swedish Cancer Society, the Swedish Childhood Cancer Fund, and Karolinska Institutet. Dr Rudd’s team is placed within SciLifeLab , a national centre for molecular biosciences containing state-of-the-art high-throughput technology platforms together with world-leading research labs focused upon cancer biology, chemical biology, and precision medicine, amongst other topics.


Your mission

The project is centred upon investigating metabolic pathways inside cancer cells, with a particular focus upon genome stability and nucleotide metabolism, and the relationship of these pathways to cancer biology and therapy resistance. The successful candidate will employ an array of biochemical, molecular and cell biology-focused approaches, together with cross-disciplinary collaborations, to fulfil the translational research goals of this project, which is to ultimately improve cancer treatment.

See Dr Rudd’s group page or website for more information, together with selected publications: Rudd et al., 2020, EMBO Mol Med ; Herold et al., 2017 Nat Med ; Tsesmetzis et al., 2018, Cancers ; Rudd et al., 2016, DNA Repair.


Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent.

We are looking for an ambitious, highly motivated and independent postdoctoral researcher (recent graduate) with a solid background in molecular biology and/or biochemistry. 

Other requirements of the position include:

  • Keen interest in translational cancer research and enzyme function
  • Well-versed with standard biochemical, molecular and cell biology techniques
  • First author publication/preprint
  • Effective communication skills – written and oral. Fluency in English.
  • Ability to work in a team

Desired skills:

  • Research experience in genome stability, cancer metabolism, nucleotide metabolism
  • Experience with high-throughput experimental approaches
  • Experience with preclinical cancer models
  • Experience in bioinformatics

This employment is for two years for a start.


What do we offer?

Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.

Location: SciLifeLab


Application

An employment application must contain the following documents in English:

  • A complete CV (including full list of publications)
  • A motivation letter
  • A summary of previous and current work (one page maximum)
  • Contact details of 2 scientists that could provide reference letters
  • Welcome to apply at the latest 2021-04-17.

    The application is to be submitted through the Varbi recruitment system.


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