Do you want to contribute to top quality medical research?
Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.
A postdoctoral position is available in the lab of Carl M. Sellgren at the department of Physiology and Pharmacology at Karolinska Institutet. Sellgren lab is located in Biomedicum, a new interdisciplinary research center designed to concentrate much of the experimental research conducted at Karolinska Institutet Campus Solna. Our research focuses on developing induced pluripotent stem cell (iPSC)-derived cellular 3D models to study neurodevelopmental disorders. For this purpose we use patient-derived cells collected at clinics in Stockholm and Massachusetts General Hospital (Boston). The research is well funded from e.g. Marianne and Markus Wallenbergs Stiftelse, One Mind Foundation, the Swedish Research Council, Stockholm County, and Erling Perssons Stiftelse. The research environment is international and we have close collaborations with laboratories world-wide.
The postdoctoral fellow will together with an experienced PhD student focus on analyses of patient-derived cerebral organoids using techniques such as scRNA sequencing, scATAC-sequencing, and spatial transcriptomics. Dependent on background, the fellow can also be involved in generating the organoids as well as in targeted gene editing and functional assays.
Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant's main supervisor, director or equivalent. We are seeking a highly motivated and independent postdoctoral researcher with a background in Single cell transcriptomics. The postdoctoral fellow will work in close collaboration with other fellows and students in the lab, utilizing the organoid platform, and collaborative skills will be highly important for success in carrying out the planned research. Below is listed experience and skills that will be considered:
- Proficiency in statistical and programming languages such as R/Python.
- Experience working in a Linux-based high-performance computing environment.
- Prior experience with analysis of single-cell omics data or other genomic sequencing data.
- Sound understanding of single-cell biology, recent technologies and data science.
- Experience with wet-lab scRNAseq protocols such as 10X genomics or SMARTseq (preferred but not needed).
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.
The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.
Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.
An application must contain the following documents in English or Swedish:
- A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
- A complete list of publications
- A summary of current work (no more than one page)
The application is to be submitted on the Varbi recruitment system.
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