Clinical Research Fellow

Updated: about 1 month ago
Location: Oxford, ENGLAND

We are seeking a Clinical Research Fellow to join Professor Jack Satsangi and Dr Oliver Brain and contribute to an established research programme aimed at understanding the pathogenesis, and stratifying the care of patients with inflammatory bowel disease for biological therapy. The studies will be performed in the Translational Gastroenterology Unit, John Radcliffe site.

Building on current  work from the  EPIC Consortium, and our previous studies in  the IBD-BIOM and IBD-CHARACTER Consortia, the post holder will develop assays for epigenetic, proteomic, and glycomic biomarkers that predict the clinical course in inflammatory bowel disease, including severe colitis and also predict primary and secondary response/non-response to biological agents, including anti-TNF therapy and apply these in samples from patient cohorts. The post holder interacts with clinical and non-clinical scientists, and members of the biobanking teams and provides guidance to less experienced members of the research group, including postdocs, research assistants, technicians, and PhD and project students.

The post will suit either a clinician, in order to provide a basis for developing research skills before applying for a research training fellowship; or an experienced trainee with a higher degree nearing/ having reached accreditation who wishes to develop their knowledge in translational medicine, and apply for an intermediate fellowship, or academic positions. Opportunities are available for developing projects either in biomarker discovery, or in basic science, to understand the biological relevance of markers identified with a view to target discovery, with a series of collaborations in place.

The appointee will interact with clinicians and scientists across the campus in Oxford. Strong support will be given for developing further scientific work. The post holder will hold a relevant medical degree: Bachelor of Medicine and Bachelor of Surgery or equivalent. An active interest in translational research with respect to optimizing the use of new agents in chronic disease, by personalization of care and GMC registration is essential. Clinical background in gastroenterology or infectious disease at SpR level is desirable.

 This post is full time and fixed-term for 12 months.

Applications for this vacancy are to be made online. You will be required to upload a supporting statement and CV as part of your online application.

Only applications received before 12.00 midday on 17 May 2021 will be considered.


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